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Ultrasonic imaging with molecular analysis


MoleculUS is a dual-modality ultrasound and photoacoustic data acquisition unit based on parallel ultrasound and photoacoustic channels sharing the same probe elements. The analog signal path of MoleculUS is split into PA and US paths. PA and US modes operate sequentially in time with support for US preview mode and continuous on-fly multiplexing between modes. For PA mode data acquisition, a dedicated preamplifier with high input impedance and fixed 40 dB gain is integrated after the input connector. MoleculUS can use linear, convex, and endocavity handheld probes. Software SDK and user interface are written in MATLAB® (compiled and source code versions); the back-end is a compiled C++ 64-bit DLL library.


  1. Compact housing and USB PC connection for easy instrument integration
  2. Standard clinical, preprogrammed ultrasound (US) modes with toggle on/off photoacoustic (PA) mode
  3. PA mode utilizes optimized broadband preamplification
  4. Integrated TR switching between high voltage, transmit/receive US beamformer and low voltage, receive only PA optimized electronics
  5. Access to raw RF data for both US and PA modes
  6. Sync external hardware with data acquisition using electronic or optical IN/OUT trigger ports
  7. Standalone control software based on MATLAB® and backend SDK written in C++ compatible with many frontend languages such as LabView, MATLAB® and PythonTM

Technical Specifications

  • 128 USPA channels

  • 41 to 91 dB PA Mode programmable gain

  • 1 to 18 MHz Transducer Center Frequency

  • 40 MSPS sampling rate

  • PA Mode Input Impedance 40 kΩ

  • Cannon QLC-260 Input Connector

  • Available US Modes: B, B+B, 4B, B+M, M, B-steer, compound, virtual convex, parallel beamforming, expanded view angle, color doppler (CFM), pulse wave (PW), duplex (B+PW), Triplex (B+CFM+PW), tissue harmonic imaging (THI)


  • Ultrasonics

  • Photoacoustics (optoacoustics)