M3™ compact and affordable MRI

  • Overview
  • Features
  • Technical Details
  • Application
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The M3™ compact, high-performance, one-touch MRI system is the smallest of Aspect Imaging’s M-series and is intended for dedicated imaging of mice. The M3™  enables to generate high-resolution 3D anatomical, functional and molecular images with a “bore” size optimized for mice. The M3™ ’s small bore correlates to a smaller total size (footprint), lighter weight, and lower MRI machine cost. The system can be uniquely placed behind the bio-containment barrier for in vivo imaging. In addition to its comprehensive suite of applications for mouse phenotyping, Aspect Imaging’s LumiQuant™ package for generation of 3D tomographic quantification of luminescence and co-registration with compact MR is optimized for use on the M3™ platform.

One instrument, multiple applications

The M3 has all the capabilities to routinely and repeatedly quantify phenotypes in mouse models of disease, including:

  • Cancer
  • Cardiovascular
  • Contrast-based Molecular Imaging
  • Diabetes and Obesity
  • Embryology / Developmental Biology
  • Nephrology
  • Neurobiology
  • Stem Cell / Cell Tracking

3D Whole Body Morphological Imaging

The M3 compact, high-performance MRI system enables high-resolution 3D whole body morphological imaging of mouse models of disease. Biologists and researchers without prior MR or imaging experience can now leverage the gold standard modality – MRI – for morphological imaging. The M3 is an in vivo imaging platform that is:

  • Easy to learn,
  • Effortless to operate, and
  • Fast to generate reproducible, quantitative results of phenotypes and therapeutic efficacy.


The M3, like the whole family of M-series magnets, provides a high-performance in vivo MRI system that is virtually maintenance free. The system requires:

  • No cryogens
  • No auxiliary power**, and
  • No compressors or plumbing that require servicing

**The M3 system only requires 1x 15 Amp outlet with 30 Amp receptacle.


The M3, like all compact MRI systems from Aspect Imaging, can be placed in most locations in a facility and doesn’t require an infrastructure typically needed with superconducting MRI system or cryogen-free MRI systems. The system therefore does not require any of the following:

  • No shielding
  • No auxiliary power supplies or services
  • No plumbing, pumps or compressors

The M3 can therefore be placed:

  • In a small animal core imaging facility
  • Right next to other modalities like PET, CT or optical
  • In a working lab
  • Behind the barrier

Technical Specifications

Product specifications are subject to change without prior notice.

Application Oriented Imaging

  • Anatomy and Morphology – In vivo soft tissue imaging for morphological characterization. 2D and 3D imaging can be performed quickly and easily for pre-clinical model assessment.
  • Cancer Research – Detection, follow-up, and quantification of tumor development and progression.
  • Neurobiology – In vivo anatomical imaging of the brain, spine and spinal cord for assessment and follow-up of neurologically-based diseases.
  • Molecular Imaging Using Contrast Agents – Detection and quantification of cellular activity targeted and enhanced with contrast agents.
  • Ex vivo Imaging – High-resolution, high throughput, 3D MR-based histology imaging of fixed samples and embryos for toxicological and developmental studies.
  • Multi-modality Imaging – Easy registration with other modalities such as Optical, PET, SPECT and CT to enable powerful multi-modality phenotyping.

Spin echo with the following options:

  • Respiration/cardiac triggering
  • Preceding inversion recovery pulse
  • Diffusion weighted imaging

Gradient echo with the following options:

  • 2D and 3D
  • Respiration/cardiac triggering
  • Dynamic acquisition – i.e. Dynamic Contrast Enhanced (DCE)
  • IR Snap for T1 map generation

Fast spin echo:

  • 2D and 3D Respiration/cardiac triggering variable echo train length
  • Multi-point fat/water separation

Small animal physiological monitoring:

  • Respiration, ECG and temperature monitoring
  • Respiration and ECG output triggering to MRI spectrometer

Isoflurane-based anesthesia:

  • Vaporizer with temperature and flow-rate compensation
  • Scavenging cube for waste gas
  • Breathing circuit with 3 access points

* for more details please download our applicant overview in the download area